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Jean-Charles Soria, Amgen’s senior vice president of Oncology within Global Development, shared an article on X:
“Cancer cachexia equals to an underdiagnosed, lethal syndrome.
- Affects up to 80% in pancreatic CA, 40% in lung.
- It’s not just weight loss—think systemic inflammation, altered metabolism, fat/muscle wasting.
- GDF-15, IL-6, activin A are key molecular drivers.
- A major unmet need in cancer patients.”
Title:?Cancer-Associated Cachexia: Bridging Clinical Findings with Mechanistic Insights in Human Studies
Authors:?Kexin Koh, Rachel Scott, Elizabeth M. Cespedes Feliciano, Tobias Janowitz, Marcus D. Goncalves, Eileen P. White, Barry J.A. Laird, Kerstin Haase, and Mariam Jamal-Hanjani
Read The Full Article at Cancer Discovery.
More posts featuring?Jean-Charles Soria.
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December 6-8, 2024
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ESMO 2024 Congress
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ASCO Annual Meeting
May 30 - June 4, 2024
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Yvonne Award 2024
May 31, 2024
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OncoThon 2024, Online
Feb. 15, 2024
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023
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